Matt Maciejewski, PhD

About

Building something new at the intersection of AI & biotech; teaching machines teach us new biology.

I also consult in data science, bioinformatics/comp bio, cheminformatics/comp chem, and run a computational CRO providing hands-on analysis, coding, and technical execution. Reach out directly if interested in collaboration.

Recently designed the first RNA editing oligonucleotide drug candidate from Korro Bio, currently in clinical trials. Throughout my career (including Pfizer, Novartis, NIH), I have used machine learning and probabilistic modeling to improve our understanding of diseases and design new treatments.

Work and Education

More complete info available on LinkedIn

Industrial Experience

• Founder, January 2025 - Present
  Stealth Mode Biotech, Cambridge MA

• Founder and CEO, January 2025 - Present
  Computational CRO & consulting services, Cambridge MA

• Vice President, Head of Data Science, June 2022 - December 2024
  Korro Bio, Cambridge MA

• Head of Data Science, December 2014 - May 2022
  Pfizer Inc., Cambridge MA

• Founder and CEO at DrugRev, 2014 - 2019

• Presidential Postdoctoral Fellow, May 2013 - November 2014
  Novartis Institutes for BioMedical Research, Cambridge MA

• Co-founder and CTO at DocDx, November 2012 - September 2014

Academic Experience

• Visiting Postdoctoral Researcher, May 2012 - May 2013
  University of Cambridge, Cambridge UK
  and University of Edinburgh, Edinburgh UK

PhD

• Wellcome Trust - NIH scholarship for collaborative graduate research,
  October 2008 - May 2012

• Graduate Researcher at Tjandra Lab
  National Institutes of Health, Bethesda MD

• PhD Candidate at Barlow Lab
  University of Edinburgh, Edinburgh UK

• Thesis "Structure and Dynamics of Proteins that Inhibit Complement Activation"

Undergraduate

BSc, 1^st Class Honors, 2008
University of Edinburgh, Edinburgh UK

Music

Before I went to university, music was a huge part of my life. Who knows, maybe one day I'll give it another shot.

Mind Gate

Through high school (and the first two years of university), I played guitar in a band called Mind Gate. In its lifetime, Mind Gate gave a bunch of concerts, interviews, and most importantly, released three demo albums.

Our final demo (called "Spiral") was officially released by an Italian record label company, Lucretia Records, and is still available on Amazon. There's also a lot of Mind Gate music available on our Myspace page - I think two whole albums - and there's a fan video on Youtube (!). Enjoy!